Co-existence of Dihydrofolate Reductase (dhfr108) Gene with Plasmodium falciparum Chloroquine Resistance Transporter Gene (Pfcrt T76) in P. falciparum Isolates from Gezira State, Central Sudan~!2009-07-01~!2009-09-06~!2010-05-11~!
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چکیده
منابع مشابه
New haplotypes of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene among chloroquine-resistant parasite isolates.
Mutations in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene were examined to assess their associations with chloroquine resistance in clinical samples from Armopa (Papua) and Papua New Guinea. In Papua, two of the five pfcrt haplotypes found were new: SVIET from Armopa and CVIKT from an isolate in Timika. There was also a strong association (P < 0.0001) between the pf...
متن کاملpfcrt gene in plasmodium falciparum field isolates from muzaffargarh, pakistan
background : the aim of the study was to identify the prevalence of different species of plasmodium and haplotypes of pfcrt in plasmodium falciparum from the selected area. methods : overall, 10,372 blood films of suspected malarial patients were examined microscopically from rural health center sinawan, district muzaffargarh, pakistan from november 2008 to november 2010. p. falciparum positive...
متن کاملPfcrt Gene in Plasmodium falciparum Field Isolates from Muzaffargarh, Pakistan
BACKGROUND The aim of the study was to identify the prevalence of different species of Plasmodium and haplotypes of pfcrt in Plasmodium falciparum from the selected area. METHODS Overall, 10,372 blood films of suspected malarial patients were examined microscopically from rural health center Sinawan, district Muzaffargarh, Pakistan from November 2008 to November 2010. P. falciparum positive s...
متن کاملFull-Length Sequence Analysis of Chloroquine Resistance Transporter Gene in Plasmodium falciparum Isolates from Sabah, Malaysia
Chloroquine resistance (CQR) in falciparum malaria was identified to be associated with several mutations in the chloroquine resistance transporter gene (pfcrt) that encodes the transmembrane transporter in digestive vacuole membrane of the parasite. This study aimed to investigate the point mutations across the full-length pfcrt in Plasmodium falciparum isolates in Sabah, Malaysia. A total of ...
متن کاملRESISTANCE OF PLASMODIUM FALCIPARUM TO CHLOROQUINE IN SOUTH EASTERN IRAN
In vivo and in vitro assessments of the response of P. falciparum to chloroquine using WHO standard kits and techniques were carried out in I ran Shahr, Sistan and Baluchestan province of Iran in 1985. In the in vivo assessment, 24 malaria patients treated with chloroquine (25mg/kg over three days) were followed up for one to four weeks. The mean parasite clearance time was 4.3 days and in...
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ژورنال
عنوان ژورنال: The Open Tropical Medicine Journal
سال: 2010
ISSN: 1874-3153
DOI: 10.2174/1874315301003010015